Pathophysiology Of Breast Cancer 106x17

Pathophysiology of ischemic Stroke

Predisposing (nonmodifiable)  Gender: Female  Age  Race: White women  Genetic  Family history  Reproductive history

Precipitating (modifiable)      

Lifestyle Alcohol use Smoking High fat diet Obesity Environmental pollutants

Etiology UNKNOW N

Vascular spasm Blood stasis and coagulability Formation of blood clot/plaque Occlusion by major vessels/arteries Increase resistance and pressure Vascular wall becomes weakened and fragiile Dislodging blood clot Emboli

Lodges and obstruct to other small vessels of tissue

vasospasm and arteries

Ventricles dilate to the site of obstruction Cerebral hypoperfusion Increase I Distribution of O2

dizziness

and glucose compression of tissues

A head ache tissue hypoxia and cellular starvation Cerebral A Schemia Impaired perfusion and function Middle Cerebral

Compression of nerves if there’s invasion of

skin & nipple retraction/dimpling microorganism & tumor obstruction

Inflammation Nipple discharges Reddened skin, local tenderness/ pain, warmth

B

B Cell breaks out & invades to lymph nodes and blood vessels Dissemination and entry to lymph and blood vessels Cancer cell lodge in lymph nodes and grows Lymph nodes and vessels become obstructed Blockage of lymph vessels draining swelling of lymph nodes fluids from the breast

inflammation and Pain

Obstruction and accumulation lymphatic of fluid Pitting of skin (similar to the surface of an orange “Peau d’orange”