SYSTEMIC PATHOLOGY SBD 2214
Pn Azrina Zainal Abidin
Quizzes (5) Assignments (2) Lab + Lab Test Mid Sem Exam Final Sem Exam
= 10% = 10% = 10% = 30% = 40%
PATHOLOGY • Definition: study of disease.
• Provide an understanding of disease processes encountered, their incidence, causes (aetiology), pathogenesis, clinical effects (sign and symptom), prognosis and their morphological appearance. • Pathology constitutes a logical and scientific basis of medicine.
Characteristics of Disease • Definition • Clinical features / sign & symptoms • Clinical finding / lab finding / histo pathological finding. • Etiology • Pathogenesis • Complication • Methods of diagnosing • Treatment • Prognosis
• Incidence: Measure of the risk of developing some new condition within a specified period of time. • Etiology: Science that deals with the causes or origin of disease, the factors which produce or predispose toward a certain disease or disorder • Pathogenesis: The development of a disease. The origin of a disease and the chain of events leading to that disease.
– Symptom • experienced and reported by the patient. • Eg : Ascites (fluid in the abdomen) Cachexia (loss of weight, muscle atrophy) Caput medusae (dilated umbilical veins) Clubbing (deformed nails) – Sign • discovered by the physician during examination of the patient
– Prognosis • doctor's prediction of how a patient's disease will progress, and whether there is a chance of recovery.
– Clinical finding • Abnormal findings in any of body specimen. • Eg: abnormal findings in urine; Chyluria, Myoglobinuria, Biliuria, Haemoglobinuria, Acetonuria – Histo pathological finding • Abnormal findings in any of body specimen through examination of a biopsy or surgical specimen by a pathologist after the specimen has been processed and histological sections have been placed onto glass slides.
– Complication • a disease or disorder arising as a consequence of another disease
Learning Resources a) Textbooks: – Harsh Mohan. Textbook of Pathology. 2005. Jaypee. – Chandrasoma, P.Taylor, C.R. 2001. Consice Pathology. 3rd edition. Mc-Graw-HillBook.
b) laboratory – Glass slides